Publikationen der ABCSG 2020-2016
Finden Sie hier eine Übersicht zu peer-reviewed Fachpublikationen (Vollpublikationen), an denen die ABCSG maßgeblich beteiligt war
Prognostic Value of EndoPredict in Women with Hormone Receptor-Positive, HER2-Negative Invasive Lobular Breast Cancer
Sestak I, Filipits M, Buus R, Rudas M, Balic M, Knauer M, Kronenwett R, Fitzal F, Cuzick J, Gnant M, Greil R, Dowsett M, Dubsky P
Clinical Cancer Research, Sep 2020
More is not always better-what can be learned from the D-CARE trial.
Pfeiler G, Gnant M.
Ann Transl Med. 2020 Aug;8(16):1034. doi: 10.21037/atm.2020.04.31.
Primary surgery versus no surgery in synchronous metastatic breast cancer:
patient-reported quality-of-life outcomes of the prospective randomized multicenter ABCSG-28 Posytive Trial
V. Bjelic-Radisic , F. Fitzal, M. Knauer, G. Steger, D. Egle, R. Greil, P. Schrenk, M. Balic, Ch. Singer, R. Exner, L. Soelkner, Michael Gnant and on behalf of the ABCSG
BMC Cancer 2020. DOI: 10.1186/s12885-020-06894-2
Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor-positive Early Breast Cancer: Results from the ABCSG Trial 5.
Bago-Horvath Z, Rudas M, Singer CF, Greil R, Balic M, Lax SF, Kwasny W, Hulla W, Gnant M, Filipits M.
Clin Cancer Res. 2020 Nov 1;26(21):5682-5688. doi: 10.1158/1078-0432.CCR-20-0673. Epub 2020 Jun 16.
Influence of a Structured Exercise Training on Patients Reported Quality of Life in Colorectal Cancer Patients After Adjuvant Chemotherapy: A Pilot Study.
Piringer G, Holzner B, Mayrbaeurl B, Heibl S, Sztankay M, Frantal S, Gnant M, Thaler J.
Integr Cancer Ther. 2020 Jan-Dec; 19:1534735420938458. doi: 10.1177/1534735420938458.
Efficacy and Safety of the Therapeutic Cancer Vaccine Tecemotide (L-BLP25) in Early Breast Cancer: Results From a Prospective, Randomised, Neoadjuvant Phase II Study (ABCSG 34)
Christian F Singer, Georg Pfeiler, Michael Hubalek, Rupert Bartsch, Herbert Stöger, Angelika Pichler, Edgar Petru, Vesna Bjelic-Radisic, Richard Greil, Margaretha Rudas, Muy-Kheng Maria Tea, Viktor Wette, Andreas L Petzer, Paul Sevelda , Daniel Egle , Peter C Dubsky , Martin Filipits, Florian Fitzal, Ruth Exner, Raimund Jakesz , Marija Balic , Christoph Tinchon, Zsuzsanna Bago-Horvath, Sophie Frantal, Michael Gnant, Austrian Breast & Colorectal Cancer Study Group
Eur J Cancer 2020 Jun;132:43-52. doi: 10.1016/j.ejca.2020.03.018. Epub 2020 Apr 20.
The EndoPredict Score Predicts Response to Neoadjuvant Chemotherapy and Neoendocrine Therapy in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-negative Breast Cancer Patients From the ABCSG-34 Trial
Peter C Dubsky, Christian F Singer , Daniel Egle , Viktor Wette , Edgar Petru , Marija Balic , Angelika Pichler , Richard Greil, Andreas L Petzer , Zsuzsanna Bago-Horvath, Christian Fesl , Stephanie M Meek, Ralf Kronenwett , Margaretha Rudas , Michael Gnant , Martin Filipits , Austrian Breast and Colorectal Cancer Study Group
Eur J Cancer 2020 Jun 2;134:99-106. doi: 10.1016/j.ejca.2020.04.020.
Long-term (up to 16 months) health-related quality of life after adjuvant tailored dose-dense chemotherapy vs. standard three-weekly chemotherapy in women with high-risk early breast cancer.
Brandberg Y, Johansson H, Hellström M, Gnant M, Möbus V, Greil R, Foukakis T, Bergh J; Swedish Breast Cancer Group, the Austrian Breast, Colorectal Cancer Study Group, the German Breast Cancer Group.
Breast Cancer Res Treat. 2020 May;181(1):87-96. doi: 10.1007/s10549-020-05602-9. Epub 2020 Mar 31.
Endocrine therapy with or without whole breast irradiation in low-risk breast cancer patients after breastconserving surgery: 10-year results of the Austrian Breast and Colorectal Cancer Study Group 8A trial
Gerd Fastner, Felix Sedlmayer, Joachim Widder, Martina Metz, Hans Geinitz, Karin Kapp, Christian Fesl, Lidija Sölkner, Richard Greil, Raimund Jakesz, Werner Kwasny, Dietmar Heck, Vesna Bjelic-Radisic, Marija Balic, Herbert Stöger, Ursula Wieder, Ronald Zwrtek, Dagmar Semmler, Wilfried Horvath, Elisabeth Melbinger-Zeinitzer, Martin Wiesholzer, Viktor Wette, Michael Gnant
European Journal of Cancer, published online 18 January 2020
Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
Cristina Saura, Dominik Hlauschek, Mafalda Oliveira, Dimitrios Zardavas, Anita Jallitsch-Halper, Lorena de la Peña, Paolo Nuciforo, Alberto Ballestrero, Peter Dubsky, Janine M Lombard, Peter Vuylsteke, Carlos A Castaneda, Marco Colleoni, Giuliano Santos Borges, Eva Ciruelos, Monica Fornier, Katalin Boer, Aditya Bardia, Timothy R Wilson, Thomas J Stout, Jerry Y Hsu, Yi Shi, Martine Piccart, Michael Gnant, José Baselga, Evandro de Azambuja
Lancet Oncology, published online August 8, 2019.
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30334-1/fulltext
Prediction of distant recurrence using EndoPredict amon women with ER+, HER2- node-positive and node-negative breast cancer treated with endocrine therapy only
Martin Filipits, Peter Dubsky, Margaretha Rudas, Richard Greil, Marija Balic, Zsuzsanna Bago-Horvath, Christian F. Singer, Dominik Hlauschek, Krystal Brown, Ryan Bernhisel, Ralf Kronenwett, Jonathan M. Lancaster, Florian Fitzal, and Michael Gnant
Clinical Cancer Research, published online May 7, 2019.
https://www.ncbi.nlm.nih.gov/pubmed/31064782
Stromal coexpression of uPA/PAI-1 protein predicts poor disease outcome in endocrine-treated postmenopausal patients with receptor-positive early breast cancer
Christian F. Singer, Martin Filipits, Stephan W. Jahn, Luca Abete, Raimund Jakesz, Richard Greil, Thomas Bauernhofer, Werner Kwasny, Michael Seifert, Florian Fitzal, Marie-Therese Kastner, Manfred Schmitt, Farid Moinfar, Michael Gnant
The Breast, veröffentlicht online am 03. Mai 2019.
https://www.ncbi.nlm.nih.gov/pubmed/31132475
Prediction of chemotherapy benefit by EndoPredict in patients with breast cancer who received adjuvant endocrine therapy plus chemotherapy or endocrine therapy alone
Ivana Sestak, Miguel Martín, Peter Dubsky, Ralf Kronenwett, Federico Rojo, Jack Cuzick, Martin Filipits, Amparo Ruiz, William Gradishar, Hatem Soliman, Lee Schwartzberg, Richard Buus, Dominik Hlauschek, Alvaro Rodríguez‑Lescure, Michael Gnant
Breast Cancer Research and Treatment published online April 2019
https://www.ncbi.nlm.nih.gov/pubmed/31041683
Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials
Early Breast Cancer Trialists’ Collaborative Group (EBCTCG)
The Lancet 2019 published online February 7, 2019.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)33137-4/fulltext
Adjuvant denosumab in postmenopausal patients with hormone receptor-positive breast cancer (ABCSG-18): disease-free survival results from a randomised, double-blind, placebo-controlled, phase 3 trial
Michael Gnant, Georg Pfeiler, Günther G Steger, Daniel Egle, Richard Greil, Florian Fitzal, Viktor Wette, Marija Balic, Ferdinand Haslbauer, Elisabeth Melbinger-Zeinitzer, Vesna Bjelic-Radisic, Raimund Jakesz, Christian Marth, Paul Sevelda, Brigitte Mlineritsch, Ruth Exner, Christian Fesl, Sophie Frantal, Christian F Singer, on behalf of the Austrian Breast and Colorectal Cancer Study Group
Lancet Oncol 2019 published online February 2019.
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30862-3/fulltext
Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials
Early Breast Cancer Trialists’ Collaborative Group (EBCTCG)
The Lancet, veröffentlicht online am 7. Februar 2019.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)33137-4/fulltext
A Phase II Randomized Study of Neoadjuvant Letrozole Plus Alpelisib for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer (NEO-ORB)
Ingrid A. Mayer, Aleix Prat, Daniel Egle, Sibel Blau, J. Alejandro Perez Fidalgo, Michael Gnant, Peter A. Fasching, Marco Colleoni, Antonio C. Wolff, Eric P. Winer1, Christian F. Singer, Sara Hurvitz, Laura Garcia Estevez, Peter A. van Dam, Sherko Kümmel, Christoph Mundhenke, Frankie Holmes, Naveen Babbar, Laure Charbonnier, Ivan Diaz-Padilla, Florian D. Vogl, Dalila Sellami, Carlos L. Arteaga
Clin Cancer Res, published online February 5, 2019.
https://www.ncbi.nlm.nih.gov/pubmed/30723140
Konferenz-Beiträge 2019
Prevention and management of residual breast tissue following therapeutic and prophylactic radical mastectomy and skin-sparing and nipple-sparing mastectomy (POSTER)
Christine Deutschmann, Georg Pfeiler
San Antonio Breast Cancer Symposium, Dezember 2019
https://cancerres.aacrjournals.org/content/80/4_Supplement/OT3-06-01
Exploratory analysis of the effect of taselisib on downstream pathway modulation and correlation with tumor response in ER-positive/HER2-negative early-stage breast cancer from the LORELEI (Poster)
Paolo Nuciforo, Dominik Hlauschek, Cristina Saura, Evandro de Azambuja, Roberta Fasani, Patricia Villagrasa, Karoline Muehlbacher, Christos Sotiriou, Aleix Prat, Georg Pfeiler, Florentine Hilbers, Timothy R. Wilson, Junko Aimi, Thomas Stout, Vicente Valero, Christian Fesl, Jose Baselga, Michael Gnant, Martine Piccart, Fabrice Andre
2019 ASCO Annual Meeting, Juni 2019
https://ascopubs.org/doi/abs/10.1200/JCO.2019.37.15_suppl.1050
Oncoplastic Breast Consortium consensus conference on nipplesparimg mastectomy
Weber W P, Haug M, Kurzeder Ch, Bjelic-Radisic V, Koller R, Reitsamer R, Fitzal F, Biazus J, Brenelli F, Urban C, Paulinelli R R, Blohmer JU, Heil J, Hoffmann J, Matrai Z, Catanuto G, Galimberti V, Gentilini O, Barry M, Hadar T, Allweis T M, Olsha O, Cardoso M J, Gouveia P F, Rubio I T, de Boniface J, Svensjö T, Bucher S, Dubsky P, Farhadi J, Fehlr M K, Fulco I, Ganz-Blättler, Günthert A, Harder Y, Hauser N, Kappos E A, Knauer M, Landin J, Mechera R, Meani F, Montagna G, Ritter M, Saccilotto R, Schwab F D, Steffens D, Tausch Ch, Zeindler J, Soysal S D, Lohsiriwat V, Kovac T, Tansley A, Wyld L, Romics L, El-Tamer M, Pusic A L, Sacchini V, Gnant M
Breast Cancer Research and Treatment
doi: 10.1007/s10549-018-4937-1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245050/
High Accumulation of Metformin in Colonic Tissue of Subjects With Diabetes or the Metabolic Syndrome
Paleari L, Burhenne J, Weiss J, Foersch S, Roth W, Parodi A, Gnant M, Bachleitner-Hofmann T, Scherer D, Ulrisch C M, Stabuc B, Pununtoni M, Coccia G, Petrera M, Haefeli W E, Decensi A
Gastroenterology
doi: 10.1053/j.gastro.2017.12.040
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002843/
TP53 is not a prognostic marker—clinical consequences of a generally disregarded fact
Braunschmid T, Kührer I, Mittlböck M, Westerhoff M, Kappel-Latif Sonja, Brammen L, Krishnadath K K, Phillips W A, Gnant M, Kandioler D
Annals of the New York Academy of Sciences
doi: 10.1111/nyas.13947
https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/nyas.13947
Toward a Consensus on Centralization in Surgery
Vonlanthen R, Lodge P, Barkun J S, Farges O, Rogiers X, Soreide K, Kehlet H, Reynolds J V, Käser S A, Naredi P, Borel-Rinkes I, Biondo S, Pinto-Marques H, Gnant M, Nafteux P, Ryska M, Bechstein W O, Martel G, Dimick J B, Krawczyk M, Oláh A, Pinna A D, Popescu , Puolakkainen P A, Sotiropoulos G C, Tukiainen E J, Petrowsky H, Clavien AP
Annals of Surgery
doi: 10.1097/SLA.0000000000002965
https://insights.ovid.com/pubmed?pmid=30169394
Postmastectomy Radiation Therapy in Women with T1-T2 Tumors and 1 to 3 Positive Lymph Nodes: Analysis of the Breast International Group 02-98 Trial
Zeidan Y H, Habib J G, Ameye L, Paesmans M, de Azambuja E, Gelber R D, Campbell I, Nordenskjöld B, Gutiérez J, Anderson M, Lluch A, Gnant M, Goldhirsch A, Di Leo A, Joseph D J, Crown J, Piccart-Gebhart M, Francis P A
International Journal of Radiation Oncology Biology Physics
doi.org/10.1016/j.ijrobp.2018.01.105
https://www.redjournal.org/article/S0360-3016(18)30230-X/pdf
Randomized clinical trial of the effect of a fibrin sealant patch on pancreatic fistula formation after pancreatoduodenectomy
Schindl M, Függer R, Götzinger P, Längle F, Zitt M, Stättner S, Kornprat P, Sahora K, Hlauschek D, Gnant M
British Journal of Surgery
DOI: 10.1002/bjs.10840
https://bjssjournals.onlinelibrary.wiley.com/doi/epdf/10.1002/bjs.10840
Association of p27 and Cyclin D1 Expression and Benefit from Adjuvant Trastuzumab Treatment in HER2-Positive Early Breast Cancer: A TransHERA Study
Filipits M, Dafni U, Gnant M, Polydoropoulou V, Hills M, Kiermaier A, de Azambuja E, Larsimont D, Rojo F, Viale G, Toi M, Harbeck N, Prichard K I, Gelber R D, Dinh P, Zardavas D, Leyland-Jones B, Piccart-Gebhart M J, Dowsett M
Clinical Cancer Research
DOI: 10.1158/1078-0432.CCR-17-3473
https://clincancerres.aacrjournals.org/content/early/2018/03/10/1078-0432.CCR-17-3473
Explained variation in shared frailty models
Gleiss A, Gnant M, Schemper M
Statistics in Medicine
DOI: 10.1002/sim.7592
https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.7592
Impact of Breast Surgery in Primary Metastasized Breast Cancer Outcomes of the Prospective Randomized Phase III ABCSG-28 POSYTIVE Trial
Fitzal F, Bjelic-Radisic V, Knauer M, Steger G, Hubalek M, Balic M, Singer Ch, Bartsch R, Schrenk P, Soelkner L, Greil R, Gnant M
Annals of Surgery
DOI: 10.1097/SLA.0000000000002771
Pathological Complete Response to Neoadjuvant Trastuzumab Is Dependent on HER2/CEP17 Ratio in HER2-Amplified Early Breast Cancer
Singer CF, Tan YY, Fitzal F, Steger GG, Egle D, Reiner A, Rudas M, Moinfar F, Gruber C, Petru E, Bartsch R, Tendl KA, Fuchs D, Seifert M, Exner R, Balic M, Bago-Horvath Z, Filipits M, Gnant M
Clinical Cancer Research doi: 10.1158/1078-0432.CCR-16-2373
https://www.ncbi.nlm.nih.gov/pubmed/28143867
St. Gallen/Vienna 2017: A Brief Summary of the Consensus Discussion about Escalation and De-Escalation of Primary Breast Cancer Treatment
Gnant M, Harbeck N, Thomssen Ch
Breast Care 2017;12:102–107 DOI: 10.1159/000475698
https://www.karger.com/Article/Fulltext/475698
Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer
von Minckwitz G, Procter M, de Azambuja E, Zardavas D, Benyunes M, Viale G, Suter T, Arahmani A, Rouchet N, Clark E, Knott A, Lang I, Levy Ch, Yardley DA, Bines J, Gelber RD, Piccart M, Baselga J
The New England Journal of Medicine DOI: 10.1056/NEJMoa1703643
https://www.nejm.org/doi/full/10.1056/nejmoa1703643
Neoadjuvant Chemotherapy with Capecitabine, Oxaliplatin and Bevacizumab Followed by Concomitant Chemoradiation and Surgical Resection in Locally Advanced Rectal Cancer with High Risk of Recurrence – A Phase II Study
Eisterer W, Piringer G, De Vries A, Öfner D, Greil R, Tschmelitsch J, Samonigg H, Sölkner L, Gnant M, Thaler J
Anticancer Research – International Journal of Cancer Research and Treatment doi:10.21873/anticanres.11xxx
https://www.ncbi.nlm.nih.gov/pubmed/28476845
20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years
Pan H, Gray R, Braybrooke J, Davies Ch, Taylor C, McGale P, Peto R, Pritchard K, Bergh J, Dowsett M, Hayes D
The New England Journal of Medicine DOI: 10.1056/NEJMoa1701830
https://www.nejm.org/doi/full/10.1056/NEJMoa1701830
Intensified preoperative chemoradiation by adding oxaliplatin in locally advanced, primary operable (cT3NxM0) rectal cancer
Kogler P, DeVries A, Eisterer W, Thaler J, Sölkner L, Öfner D
Journal of Radiation Oncology doi: 10.1007/s00066-017-1219-5
https://www.ncbi.nlm.nih.gov/pubmed/29127435
Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial
Colleoni M, Luo W, Karlsson P, Chirgwin J, Aebi S, Jerusalem G, Neven P, Hitre E, Graas MP, Simoncini E, Kamby C, Thompson A, Loibl S, Gavilá J, Kuroi K, Marth C, Müller B, O’Reilly S, Di Lauro V, Gombos A, Ruhstaller T, Burstein H, Ribi K, Bernhard J, Viale G, Maibach R, Rabaglio-Poretti M, Gelber R, Coates A, Di Leo A, Regan M, Goldhirsch A
The Lancet Oncology doi: 10.1016/S1470-2045(17)30715-5
https://www.ncbi.nlm.nih.gov/pubmed/2915801
Complexity of intermittent letrozole adjuvant therapy (Comment zu: Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial)
Chlebowski R, Pan K
The Lancet Oncology doi: 10.1016/S1470-2045(17)30854-9
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(17)30854-9/fulltext
Rethinking Extended Adjuvant Antiestrogen Therapy to Increase Survivorship in Breast Cancer
Abderrahman B, Jordan VC
JAMA Oncology doi: 10.1001/jamaoncol.2017.3510
https://jamanetwork.com/journals/jamaoncology/article-abstract/2663286
A prospective, multicenter pilot study to investigate the feasibility and safety of a 1-year controlled exercise training after adjuvant chemotherapy in colorectal cancer patients.
Piringer G, Fridrik M, Fridrik A, Leiherer A, Zabernigg A, Greil R, Eisterer W, Tschmelitsch J, Lang A, Frantal S, Burgstaller S, Gnant M, Thaler J
Support Care Cancer DOI: 10.1007/s00520-017-3961-8
https://www.ncbi.nlm.nih.gov/pubmed/29168033
Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor–Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evaluation (FACE) Trial
Smith I, Yardley D, Burris H, De Boer R, Amadori D, McIntyre K, Ejlertsen B, Gnant M, Jonat W, Pritchard K, Dowsett M, Hart L, Poggio S, Comarella L, Salomon H, Wamil B, O’Shaughnessy J
Journal of Clinical Oncology DOI: 10.1200/JCO..69.2871
Effect of Tailored Dose-Dense Chemotherapy vs Standart 3-Weekly Adjuvant Chemotherapy on Recurrence-Free Survival Among Women With High-Risk Early Breast Cancer
Foukakis T, von Minckwitz G, Bengtsson N-O, Brandberg Y, Wallberg B, Fornander T, Mlineritsch B, Schmatloch S, Singer C, Steger G, Egle D, Karlsson E, Carlsson L, Loibl S, Untch M, Hellström M, Johansson H, Anderson H, Malmström P, Gnant M, Greil R, Möbus V, Bergh J
Jama Original Investigation. ;316(18):1-9. doi:10.1001/jama..15865
Publikationen der ABCSG (peer reviewed) 2011-2015
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