ABCSG R07 / Rectal Cancer Registry: First Site Activated
ABCSG is pleased to announce that the first Austrian site for the ABCSG R07 / Rectal Cancer Registry (RCR) has been activated.
The study team at the Department of Internal Medicine III at University Hospital Salzburg – PMU, led by Co-Coordinating Investigator A.o. Univ.-Prof. Dr. Lukas Weiss and Coordinating Investigator Prim. Univ.-Prof. Dr. Falk Röder, was activated as the first Austrian site for patient enrolment on 10 September 2026. This marks the launch of the new national registry study documenting the real-world treatment landscape for patients with localized rectal cancer in Austria.
The ABCSG R07 / Rectal Cancer Registry is a multicenter, retrospective and prospective non-interventional study (NIS). Its aim is to establish a nationwide registry assessing the therapeutic management of patients with locally advanced, non-metastatic adenocarcinoma of the rectum.
The study focuses, on the one hand, on patients with microsatellite-stable disease (pMMR/MSS) who have received total neoadjuvant therapy (TNT). Although TNT represents a key treatment approach for locally advanced or distal rectal cancer, the protocols used in Austria vary between centers – for example, with regard to the sequencing of chemotherapy and radiotherapy as well as the treatment regimens used.
In addition, patients with dMMR/MSI-H disease will be included. In this patient population, the study aims to document the clinical transition from conventional treatment approaches such as chemotherapy, radiotherapy and surgery towards immunotherapy, which is on the verge of becoming the new standard of care for this patient group.
A total of 600 patients are planned to be enrolled across Austria. The Coordinating Investigator is Prim. Univ.-Prof. Dr. Falk Röder, Salzburg. The Co-Coordinating Investigators are A.o. Univ.-Prof. Dr. Lukas Weiss, Salzburg, and Priv.-Doz. Dr. Gudrun Piringer, Linz.
We are pleased to see the first site successfully activated and wish the entire study team every success for the study.
→ Further information on the ABCSG R07/ Rectal Cancer Registry
© SALK Fürweger
14.09.2026
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