{"id":38620,"date":"2025-06-13T05:50:51","date_gmt":"2025-06-13T03:50:51","guid":{"rendered":"https:\/\/www.abcsg.org\/wir-gratulieren-unserem-statistiker-dominik-hlauschek-zu-seiner-ersten-wissenschaftlichen-vollpublikation-in-esmo-open\/"},"modified":"2025-06-13T08:00:49","modified_gmt":"2025-06-13T06:00:49","slug":"wir-gratulieren-unserem-statistiker-dominik-hlauschek-zu-seiner-ersten-wissenschaftlichen-vollpublikation-in-esmo-open","status":"publish","type":"post","link":"https:\/\/www.abcsg.org\/en\/wir-gratulieren-unserem-statistiker-dominik-hlauschek-zu-seiner-ersten-wissenschaftlichen-vollpublikation-in-esmo-open\/","title":{"rendered":"Congratulations to Dominik Hlauschek on His First Full Publication in ESMO Open!"},"content":{"rendered":"<p>A proud moment for the ABCSG statistics team: our colleague Dominik Hlauschek has just published his first full paper in <em data-start=\"649\" data-end=\"660\">ESMO Open<\/em> \u2014 a key step in his scientific career. Congratulations &#8211; and many thanks to Christian Fesl for his leadership and to the whole statistics team for their support!<\/p>\n<p><!--more-->This paper critically examines the new IBCFS endpoint introduced in 2021 and its implications for statistical analyses of adjuvant breast cancer trials.<\/p>\n<p>Drawing on recent insights from the statistical community and real-world data from four large ABCSG studies, the paper illustrates how different approaches to handling second primary non-breast cancers (SPNBCs) result in different clinical interpretations, emphasizing that even standardized endpoints require careful handling.<\/p>\n<p>This publication reflects ABCSG\u2019s continued commitment not only to designing and conducting high-quality clinical trials, but also to critically re-evaluating statistical methodology and cancer guidelines in oncology research.<\/p>\n<p><strong>Future guidelines must take such statistical nuances into account &#8211; otherwise, they risk falling short of true standardization.<\/strong><\/p>\n<h4>The impact of analysis methodology details on invasive breast cancer-free survival in randomized clinical trials<\/h4>\n<p>D. Hlauschek, C. Fesl &amp; M. Gnant<\/p>\n<p>ESMO Open<br \/>\nVolume 10,\u00a0Issue 7, July 2025<br \/>\nPublished online: June 11, 2025<br \/>\n<a href=\"https:\/\/doi.org\/10.1016\/j.esmoop.2025.105324\">https:\/\/doi.org\/10.1016\/j.esmoop.2025.105324<\/a><\/p>\n<p><a href=\"https:\/\/www.abcsg.org\/wp\/wp-content\/uploads\/2025\/06\/Hlauschek-et-al-2025-ESMO-open_The-impact-of-analysis-methodology-on-IBCFS.pdf\" target=\"_blank\">Download PDF<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A proud moment for the ABCSG statistics team: our colleague Dominik Hlauschek has just published his first full paper in ESMO Open \u2014 a key step in his scientific career. Congratulations &#8211; and many thanks to Christian Fesl for his leadership and to the whole statistics team for their support!<\/p>\n","protected":false},"author":1,"featured_media":38616,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[505,595],"tags":[584],"class_list":["post-38620","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-news-2025-en","tag-50-publikationen-en"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-07 23:50:04","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/posts\/38620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/comments?post=38620"}],"version-history":[{"count":2,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/posts\/38620\/revisions"}],"predecessor-version":[{"id":38626,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/posts\/38620\/revisions\/38626"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/media\/38616"}],"wp:attachment":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/media?parent=38620"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/categories?post=38620"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/tags?post=38620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}