{"id":41126,"date":"2026-02-24T12:51:18","date_gmt":"2026-02-24T11:51:18","guid":{"rendered":"https:\/\/www.abcsg.org\/veroeffentlichungen\/publications\/publikationen-der-abcsg-2026-2025\/"},"modified":"2026-02-26T05:47:49","modified_gmt":"2026-02-26T04:47:49","slug":"publikationen-der-abcsg-2026-2025","status":"publish","type":"page","link":"https:\/\/www.abcsg.org\/en\/veroeffentlichungen\/publications\/publikationen-der-abcsg-2026-2025\/","title":{"rendered":"ABCSG-Publications (peer reviewed) 2026-2025"},"content":{"rendered":"
\n
<\/span>2026<\/div>
\n

Abstract RF7-07: Adjuvant Palbociclib for ER+ Breast Cancer in the PALLAS Trial (ABCSG-42\/AFT-05\/PrE0109\/BIG-14-13): Post-Recurrence Treatment and Overall Survival\u00a0<\/h4>\n

A. DeMichele; A. Dueck; M. Gnant; D. Hlauschek; M. Martin; A. Wolff; G. Rubovsky; F. Henao; O. Hahn; A. Chan; A. Brusky; P. Morris; H. Burstein; G. Huber; D. Anderson; L. Garcia-Estevez; G. Pfeiler; H. Rugo; N. Zdenkowski; S. Gampenrieder; N. Wolmark; D. Sabanathan; K. Miller; D. Cameron; E. Winer; C. Brunner; E. Gauthier; P. O\u2019Brien; C. Fesl; E. Mayer<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): RF7-07.
\nAvailable online 17 February 2026
\nDOI: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-RF7-07<\/a><\/p>\n

\n

Abstract PS3-08-13: Exploratory analysis of palbociclib benefit in the PALLAS trial by SETERPR\u00a0index and prior chemotherapy regimens (ABCSG-42\/AFT-05\/BIG-14-13)<\/h4>\n

O. Metzger; P. O’Brien; K. Ballman; M. Gnant; M. Watson; E. Chen; K. Tran; D. Hlauschek; M. Martin; J. Balko; Z. Nowecki; O. Hahn; C. Denkert; C. Curtis; F. Liu; A. Dueck; C. Fesl; E. Mayer; A. De Michele; W. Symmans<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): PS3-08-13.
\nAvailable online 17 February 2026
\nDOI: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-PS3-08-13<\/a><\/p>\n

\n

Abstract PS2-07-11: The improved long-term outcome in denosumab-treated postmenopausal women with early luminal breast cancer in Abcsg 18 is driven by progesterone receptor-positive tumors<\/h4>\n

C. Singer; D. Hlauschek; D. Egle; A. Reiner; G. G. Steger; G. Huber; R. Greil; G. Rinnerthaler; F. Fitzal; C. Brunner; C. Suppan; G. Pfeiler; S. P. Gampenrieder; M. Seifert; S. Kacerovsky-Strobl; C. Deutschmann; K. Wimmer; M. Balic; R. Jakesz; C. Fesl; H. Fohler; M. Gnant<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): PS2-07-11.
\nAvailable online 17 February 2026
\nDOI: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-PS2-07-11<\/a><\/p>\n

\n

Abstract PS3-04-08: Independent Validation of a Pathology-Based Multimodal Artificial Intelligence Biomarker for Predicting Risk of Distant Metastasis in Postmenopausal, Estrogen Receptor-Positive, Early-Stage Breast Cancer Patients: Analysis of the ABCSG Trial 8<\/h4>\n

M. Filipits; D. Hlauschek; J. Zhang; M. Balic; R. Kates; R. Greil; F. Fitzal; N. Toro-Bauer; G. Rinnerthaler; H. Pinckaers; K. Sotlar; Z. Bago-Horvath; W. Hulla; P. Regitnig; A. Piehler; C. E. Geyer; H. Kreipe; J. Griffin; N. Harbeck; N. Wolmark; M. Gnant<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): PS3-04-08.
\nAvailable online 17 February 2026
\nDOI: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-PS3-04-08<\/a><\/p>\n

\n

Abstract RF2-07: Nodal disease burden in patients with clinically node-positive breast cancer undergoing tailored axillary surgery with or without axillary dissection in the neoadjuvant and upfront surgery setting: pre-planned TAXIS study (OPBC-03, SAKK 23\/16, IBCSG 57-18, ABCSG-53, GBG 101)<\/h4>\n

W. P. Weber; C. Tausch; S. Hayoz; Z. Matrai; G. Xepapadakis; C. Simonson; V. Bjelic-Radisic; G. T. Lam; G. Montagna; M. Gnant; L. H. Rosenberger; E. de Bree; R. Satler; M. Fehr;\u00a0C. Leo; L. Lelievre; S. Bucher; S. Schmid; R. Exner; K. Reisenberger; U. Beckmann; S. Muenst; G. Henke; D. R. Zwahlen; T. Ruhstaller; K. Ribi; C. Urban; A. Crown; J. E. Lee; J. Boileau; A. D. Williams; Y. Jonghan; M. L. DiNome; A. Poultsidi; E. Gonzales; S. M. Wong; A. Schulz; M. Nealeigh; S. G. Ahn; A. M. Botty van den Bruele; B. J. Chae; A. Mueller; D. Hagen; J. M. Ryu; A. Savolt; C. Kurzeder; J. Heil; D. Egle; M. Heidinger; M. Knauer<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): RF2-07.
\nAvailable online 17 February 2026
\nDOI: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-RF2-07<\/a><\/p>\n

\n

Abstract PD11-01: Development of a Multi-Modal Artificial Intelligence (MMAI) Model for Predicting Distant Metastasis in HR+ Early-Stage Invasive Breast Cancer<\/h4>\n

C. E. Geyer, Jr.; D. A. Kates-Harbeck; P. Rastogi; R. Kates; M. Filipits; D. Hlauschek; C. Fesl; M. Christgen; U. Nitz; S. Kuemmel; M. Graeser; H. Christgen; O. Gluz; T. Freeman; S. Anderson; H. Pinckaers; A. Piehler; W. Zwerink; J. Zhang; S. Joun; J. Ross; C. Chao; J. Griffin; H. Kreipe; M. Gnant; N. Wolmark; N. Harbeck<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): PD11-01.
\nAvailable online 17 February 2026
\nDOI: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-PD11-01<\/a><\/p>\n

\n

Abstract RF3-03: Evaluation of a digital pathology based multimodal artificial intelligence model for prognosis and prediction of chemotherapy benefit in node-negative, hormone receptor-positive breast cancer patients: analysis of the NSABP B-20 trial<\/h4>\n

C. E. Geyer; M. Filipits; N. Harbeck; N. Harbeck; J. Zhang6; P. Rastogi; A. Piehler; T. Freeman; M. Balic; W. Zwerink; H. Kreipe; D. Hlauschek; S. Anderson; J. R. Griffin; D. Kates-Harbeck; M. Gnant; N. Wolmark<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): RF3-03.
\nAvailable online 17 February 2026
\nDOI: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-RF3-03<\/a><\/p>\n

\n

Abstract PS2-07-21: Tumor Necrosis Factor-related Weak Inducer of Apoptosis (TWEAK) – A Potential Biomarker for Predicting Response and Long-Term Outcomes in Early Breast Cancer Patients<\/h4>\n

K. Wimmer; D. Hlauschek; A. Rauch; M. Sachet; C. Ramos; V. Gerakopulos; G. Pfeiler; C. Brunner; G. Pristauz-Telsnigg; G. Rinnerthaler; A. Pichler; F. Fitzal; S. P. Gampenrieder; G. Huber; M. Seifert; D. Egle; M. Filipits; R. Oehler; C. Singer; M. Gnant; Austrian Breast & Colorectal Cancer Study Group<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): PS2-07-21.
\nAvailable 17 February 2026
\nDOI\u00a0: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-PS2-07-21<\/a><\/p>\n

\n

Abstract PS3-07-14: Predictors of early discontinuation of adjuvant palbociclib in early HR+\/ HER2- breast cancer: final analysis of the PALLAS trial integrating patient-reported outcomes<\/h4>\n

M. Vetter; A. Wiencierz; M. Gnant; D. Hlauschek; C. Kurzeder; C. Grasic Kuhar; N. Zdenkowski; E. Shinn; J. Suga; D. Egle; J. Meisel; E. Munzone; T. Haddad; S. Loibl; A. Holynskyj; C. Fesl; A. Dueck; A. DeMichele; E. Mayer\u00a0PALLAS groups and investigators (ABCSG, AFT, BIG, PReCOG, GBG, NSABP)<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement): PS3-07-14.
\nAvailable 17 February 2026
\nDOI\u00a0: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-PS3-07-14<\/a><\/p>\n

\n

Abstract PS2-07-13: Prognostic and predictive role of RBsig and CCNE1\/RB1 gene-expression signatures for patients with early breast cancer treated with endocrine therapy with or without palbociclib in the PALLAS trial (ABCSG-42, AFT-05, BIG 14-03)<\/h4>\n

L. Malorni; D. Hlauschek; E. Mayer; M. Benelli; L. Biganzoli; I. Migliaccio; A. Kermanidis; G. Pfeiler; E. P. Mamounas; A. M. Brufsky; M. Bellet-Ezquerra; K. Clifton; G. Rubovszky; T. Foukakis; M. Goetz; S. Lee; M. Ruiz-Borrego; W. Symmans; K. V. Ballman; F. Liu; J. Machacek-Link; C. Denkert; A. DeMichele; M. Gnant<\/p>\n

Clin Cancer Res\u00a0(2026) 32 (4_Supplement)\u00a0: PS2-07-13.
\nAvailable online 15 February 2026
\nDOI\u00a0: https:\/\/doi.org\/10.1158\/1557-3265.SABCS25-PS2-07-13<\/a><\/p>\n<\/div><\/div>\n

<\/span>2025<\/div>
\n

HER2\/CEP17 ratio is associated with pCR after HER2-directed neoadjuvant treatment in the phase III NeoALTTO trial<\/h4>\n

Christian F. Singer, Franz Koenig, Stephanie Kacerovsky-Strobl, Sabine Danzinger, Christine Brunner, Christoph Suppan, Christine Deutschmann, Marija Balic, Richard Greil, Daniel Egle, Evandro de Azambuja, Serena Di Cosimo, Anup Choudhury, Michael Gnant<\/p>\n

The Breast 85 (2026) 104679
\nPublished by Elsevier Ltd.
\nAvailable online 22 December 2025
\nDOI: https:\/\/doi.org\/10.1016\/j.breast.2025.104679<\/a><\/p>\n

\n

40P An artificial intelligence model predicts Ki67 from H&E-stained whole slide images in breast cancer<\/h4>\n

D. Kates Harbeck, M. Filipits, D. Hlauschek, G. Rinnerthaler, S.P. Gampenrieder, K. Haider, W.H. Hulla, R.E. Kates, H.Kreipe, M. Christgen, O. Gluz, S. Mahner, J. Zhang, H. Pinckaers, G. Smit, A. Piehler, J.R. Griffin, N. Harbeck, M.I. Gnant<\/p>\n

ESMO Real World Data and Digital Oncology
\nVolume 10,\u00a0Supplement\u00a0100239, November 2025
\nDOI: https:\/\/doi.org\/10.1016\/j.esmorw.2025.100239<\/a><\/p>\n

\n

ESR1<\/em>,\u00a0PGR<\/em>,\u00a0ERBB2<\/em>,\u00a0and\u00a0MKi67\u00a0<\/em>mRNA expression in diagnostic core biopsies from breast cancer patients of the ABCSG Trial 34<\/h4>\n

Stephanie Kacerovsky-Strobl, Christine Deutschmann, Dominik Hlauschek, Zsuzsanna Bago-Horvath, Christian F. Singer, Rupert Bartsch, Richard Greil, Karl Sotlar, Gabriel Rinnerthaler, Edgar Petru, Sigurd F. Lax, Daniel Egle, Angelika Pichler, Kopp\u00e1ny Bod\u00f3, Andreas L. Petzer, Farid Moinfar, Jodi Weidler, Michael Bates, Peter Dubsky, Michael Gnant, Martin Filipits<\/p>\n

The Breast
\nDOI: https:\/\/doi.org\/10.1016\/j.breast.2025.104633<\/a><\/p>\n

\n

Palbociclib with adjuvant endocrine therapy in early breast cancer: 5-year follow-up analysis of the global multicenter, open-label, randomized phase III PALLAS trial (ABCSG-42\/AFT-05\/PrE0109\/BIG-14-13)<\/h4>\n

E. L. Mayer, D. Hlauschek, M. Gnant, P. J. O\u2019Brien, M. Bellet-Ezquerra, M. P. Goetz, M. Ruiz-Borrego, A. Chan, K. Clifton, D. Egle, D. Lake, P. Cabrera, T. Mamounas, G. Pristauz-Telsnigg, Z. Dayao, M. Gil Gil, D. Cameron, T. Traina, P. G. Morris, D. Sabanathan, G. Rinnerthaler, J. Meisel, A. Prat, A. C. Wolff, L.-M. Tseng, C. Isaacs, C. F. Singer, G. Rubovszky, T. Foukakis, J. Jassem, E. P. Winer, M. Vetter, J. Federmann, O. Metzger, C. Schurmans, E. Gauthier, D. R. Lu, C. Fesl, A. Dueck & A. DeMichele<\/p>\n

Annals of Oncology
\nArticles in Press, October 17, 2025 – Open access
\nhttps:\/\/doi.org\/10.1016\/j.annonc.2025.10.003<\/a><\/p>\n

\n

Surgical outcome parameters in breast cancer: A survey comparing oncoplastic and non-oncoplastic surgeons as well as certified with non-certified breast health centers<\/h4>\n

Wimmer K, Gordon K, Emmanuel K, Steger G, Gnant M, Weber WP, Fitzal F<\/p>\n

Breast Care
\nPublished online: October 3
\nDOI: 10.1159\/000548657<\/a><\/p>\n

\n

Prevalence and prognosis of patients with breast cancer eligible for adjuvant abemaciclib or ribociclib: a nationwide population-based study<\/h4>\n

Xingrong Liu, Behnaz Binicy, Balazs Acs, Louise Eriksson Bergman, Sibylle Loibl, Michael Gnant, Michael Untch, Antonios Valachis, Jonas Bergh, Johan Hartman, Theodoros Foukakis and Alexios Matikasa<\/p>\n

The Lancet Regional Health – Europe 2025;59: 101471
\nAvailable online 29 September 2025
\nhttps:\/\/doi.org\/10.1016\/j.lanepe.2025.101471<\/a><\/p>\n

\n

A core outcome set for locoregional treatment reporting in neoadjuvant systemic breast cancer treatment trials<\/h4>\n

PRECEDENT Study Group,\u00a0Shelley Potter*,\u00a0Kerry N L Avery, Rosina Ahmed, Jana De Boniface, Sanjoy Chatterjee, David Dodwell, Peter Dubsky, Jingjing Federmann, Sandra Finestone, Michael Gnant, Dominik Hlauschek, Hiroji Iwata, Michael Y Jiang, Orit Kaidar-Person, Han-Byoel Lee, Mairead Mackenzie, Anne Meyn, Phillip Poortmans, Fiorita PoulakakiAndrea L Richardson, Karla A Sepulveda, Andrew J Spillane, Alastair M Thompson, Gustavo Werutsky, Philipp Wittmann, Jean L Wright, Nicholas Zdenkowski, Katherine Cowan, Stuart A McIntosh<\/p>\n

BMJ Open 2024;14:e084488.
\ndoi:10.1136\/bmjopen-2024-084488<\/a><\/p>\n

\n

New perspectives in the management of triple-negative breast cancer<\/h4>\n

Bartsch R, Bago-Horvath Z, Egle D, Gampenrieder SP, Gr\u00fcnberger B, Heibl S, Marhold M, Preuss C, Rinnerthaler G, Strasser-Weippl K, Suppan C, Singer CF, Gnant M<\/p>\n

Breast Care (2025), Published by S. Karger AG, Basel
\nPublished online: August 15, 2025
\nhttps:\/\/doi.org\/10.1159\/000547988<\/a><\/p>\n

\n

Extending the duration of endocrine treatment for early breast cancer: patient-level meta-analysis of 12 randomised trials of aromatase inhibitors in 22 031 postmenopausal women already treated with at least 5 years of endocrine therapy<\/h4>\n

Early Breast Cancer Trialists\u2019 Collaborative Group (EBCTCG)*
\n*Austrian Breast Cancer Study Group (ABCSG), Vienna, Austria – M Balic, R Bartsch, C Fesl, F Fitzal, H Fohler, M Gnant, R Greil, R Jakesz, C Marth, B Mlineritsch, G Pfeiler, C F Singer, L S\u00f6lkner, G G Steger, H Sto\u0308ger<\/p>\n

The Lancet
\nVol 406 August 9, 2025
\nhttps:\/\/doi.org\/10.1016\/S0140-6736(25)01013-X<\/a><\/p>\n

\n

Was kommt nach CDK4\/6- Inhibition? Perspektiven beim fortgeschrittenen Mammakarzinom<\/h4>\n

Vanessa Castagnaviz, Anna Fenzl, Michael Gnant, Rupert Bartsch<\/p>\n

Wiener klinische Wochenschrift
\nDFP-Fortbildung
\nPublished:\u00a031 July 2025
\nhttps:\/\/doi.org\/10.1007\/s00508-025-02582-y<\/a><\/p>\n

\n

Hormonal factors predictive of fertility in patients with breast cancer interrupting adjuvant endocrine therapy to attempt pregnancy in POSITIVE trial<\/h4>\n

Isabelle Demeestere, Samuel M. Niman, Ann H. Partridge, Daniela S. Diego, Roswitha Kammler, Monica Ruggeri, Marco Colleoni, Chikako Shimizu, Cristina Saura, Karen A. Gelmon, Anna B. Saetersdal, Judith R. Kroep, Audrey Mailliez, Frederic Amant, Manuel Ru\u0131z-Borrego, Jeong Eon Lee, Akemi Kataoka, Janice M. Walshe, Junko Takei, Simona Borstnar, Virginia F. Borges, Christobel Saunders, Snezana Susnjar, Vesna Bjelic-Radisic, Fatima Cardoso, Jane Lowe Meisel, Jennifer F. Kawwass, Tanja Spanic, Sarra El-Abed, Martine Piccart, Larissa A. Korde, Aron Goldhirsch,Richard D. Gelber, Olivia Pagani, Hatem A. Azim Jr., Fedro A. Peccatori, for the International Breast Cancer Study Group and the POSITIVE Trial Collaborators<\/p>\n

The Breast. Published by Elsevier Ltd.
\nAvailable online 26 July 2025
\nhttps:\/\/doi.org\/10.1016\/j.breast.2025.104547<\/a><\/p>\n

\n

Breastfeeding After Hormone Receptor\u2013Positive Breast Cancer: Results From the POSITIVE Trial<\/h4>\n

Fedro A. Peccatori, Samuel M. Niman, Ann H. Partridge, Monica Ruggeri, Marco Colleoni, Cristina Saura, Chikako Shimizu, Anna B. Satersdal, Judith R. Kroep, Karen Gelmon, Frederic Amant, Audrey Mailliez, Halle C.F. Moore, Manuel Ruiz-Borrego, Janice M. Walshe, Virginia F. Borges, Andrea Gombos, Akemi Kataoka, Christine Rousset-Jablonski, Simona Borstnar, Junko Takei, Jeong E. Lee, Christobel Saunders, Vesna Bjelic-Radisic, Snezana Susnjar, Fatima Cardoso, Natalie J. Klar, Teresa Ferreiro, Sarra El-Abed, Martine Piccart, Larissa A. Korde,<\/p>\n

Aron Goldhirsch, Richard D. Gelber, \u00a0Olivia Pagani, and Hatem A. Azim Jr, \u00a0for the International Breast Cancer Study Group and the POSITIVE Trial Collaborators<\/p>\n

J Clin Oncol 43:2712-2719
\nPublished July 9, 2025
\nhttps:\/\/doi.org\/10.1200\/JCO-24-02697<\/a><\/p>\n

\n

Genomic profiling of primary tumor and lymph node metastasis in patients with clinically node-positive breast cancer: Prospective cohort study within TAXIS (OPBC-03, SAKK 23\/16, IBCSG 57-18, ABCSG-53, GBG 101)<\/h4>\n

Michael\u00a0Knauer,\u00a0Daniel\u00a0Egle,\u00a0Stefanie\u00a0Hayoz,\u00a0\u00c1kos\u00a0S\u00e1volt,\u00a0Christoph\u00a0Tausch,\u00a0Susanne\u00a0Bucher,\u00a0Colin\u00a0Simonson,\u00a0Rok\u00a0Satler,\u00a0J\u00f6rg\u00a0Heil,\u00a0Inga\u00a0Bekes,\u00a0Vesna\u00a0Bjelic-Radisic,\u00a0William\u00a0Audeh,\u00a0Giang Thanh\u00a0Lam,\u00a0Andrea\u00a0Menicucci,\u00a0Simone\u00a0Muenst,\u00a0Valerijus\u00a0Ostapenko,\u00a0Christian\u00a0Kurzeder,\u00a0Martin\u00a0Heidinger,\u00a0Walter P.\u00a0Weber\u00a0<\/p>\n

European Journal of Cancer
\nAvailable online 18 June 2025, 115585
\nhttps:\/\/doi.org\/10.1016\/j.ejca.2025.115585<\/a><\/p>\n

\n

Abstract P4-01-26: The Xpert\u00ae Breast Cancer Insight test predicts distant recurrence and overall survival in estrogen receptor-positive, HER2-negative early breast cancer: A validation study in ABCSG Trial 8\u00a0<\/h4>\n

Martin Filipits; Viktoria Gruber; Christian F. Singer; Florian Fitzal; Zsuzsanna Bago-Horvath; Richard Greil; Marija Balic; Peter Regitnig; Nancy Toro-Bauer; Wolfgang Hulla; Daniel Egle; Daneida Lizarraga; Alice Baker; Rajesh Kaldate; Malini Satya; Jodi Weidler; Michael Bates;\u00a0Scott Campbell; Dominik Hlauschek; Peter Dubsky; Michael Gnant<\/p>\n

Clinical Cancer Research
\nVolume 31, Issue 12_Supplement
\n15 June 2025
\nhttps:\/\/doi.org\/10.1158\/1557-3265.SABCS24-P4-01-26<\/a><\/p>\n

\n

Abstract P2-03-30: Association of ctDNA in patients with long-term outcome of breast cancer patients undergoing neoadjuvant treatment in the randomized ABCSG 34 clinical trial\u00a0<\/h4>\n

Daniel Egle; Dominik Hlauschek; Simon Gampenrieder; Gabriel Rinnerthaler; Christian Singer; Georg Pfeiler; Rupert Bartsch; Gregor Huber;\u00a0Angelika Pichler; Edgar Petru; ZsuZsanna Bago-Horvath; Anna Kermanidis; Christian Fesl; Ricarda Graf; Sabrina Weber; Nadia Dandachi; Martin Filipits; Michael Gnant; Ellen Heitzer; Marija Balic<\/p>\n

Clinical Cancer Research
\nVolume 31, Issue 12_Supplement
\n15 June 2025
\nhttps:\/\/doi.org\/10.1158\/1557-3265.SABCS24-P2-03-30<\/a><\/p>\n

\n

Abstract PS3-03: Vaccination with MUC-1-targeting tecemotide improves Survival of patients receiving neo-adjuvant chemotherapy for early breast cancer: Results from the Prospective Randomized ABCSG 34 Trial\u00a0<\/h4>\n

Christian F. Singer; Dominik Hlauschek; Georg Pfeiler; Daniel Egle; Rupert Bartsch; Christoph Suppan; Angelika Pichler; Edgar Petru; Richard Greil;\u00a0Margaretha Rudas; Michael Seifert; Gregor Huber; Andreas Petzer; Florian Fitzal; Zsuzsanna Bago-Horvath; Martin Filipits; Lidija Soelkner; Christian Fesl; Michael Gnant<\/p>\n

Clinical Cancer Research
\nVolume 31, Issue 12_Supplement
\n15 June 2025
\nhttps:\/\/doi.org\/10.1158\/1557-3265.SABCS24-PS3-03<\/a><\/p>\n

\n

Abstract P2-01-24: Immune activation of tumor cells and microenvironment as assessed by PD-L1 expression and interferon gamma signaling predict long term disease-free and overall survival: Results of the prospective randomized neoadjuvant ABCSG 34 trial<\/h4>\n

Ulrike M. Heber; Dominik Hlauschek; Christian F. Singer; Daniel Egle; Richard Greil; Ruth Helfgott; Gregor Huber; Elisabeth M\u00fcller-Holzner;\u00a0Cornelia Hauser-Kronberger; Margaretha Rudas; Georg Pfeiler; Rupert Bartsch; Sigurd Lax; Martin Filipits; Gabriel Rinnerthaler; Michael Gnant;\u00a0Zsuzsanna Bago-Horvath<\/p>\n

Clinical Cancer Research
\nVolume 31, Issue 12_Supplement
\n15 June 2025
\nhttps:\/\/doi.org\/10.1158\/1557-3265.SABCS24-P2-01-24<\/a><\/p>\n

\n

The impact of analysis methodology details on invasive breast cancer-free survival in randomized clinical trials<\/h4>\n

D. Hlauschek, C. Fesl & M. Gnant<\/p>\n

ESMO Open
\nVolume 10,\u00a0Issue 7, July 2025
\nPublished online: June 11, 2025
\nhttps:\/\/doi.org\/10.1016\/j.esmoop.2025.105324<\/a><\/p>\n

\n

Quality-of-life and symptom severity in the PALLAS randomized trial of palbociclib with adjuvant endocrine therapy in early breast cancer (AFT-05, ABCSG-42, BIG-14-03, PrE0109)<\/h4>\n

M.J. Naughton, D.M. Zahrieh, M. Gnant, N. Zdenkowski, J. Lemieux, J.J. Mao, V. Bjelic Radisic, E. Shinn, M. Balic, C. Thomssen, J.L. Meisel, G.M. Ruiz, S. Loibl, C. Isaacs, D. Cameron, F.M. Henao-Carrasco, M.P. Goetz, C.F. Singer, G. Werutsky, H.S. Rugo, M. Vetter, L.-M. Tseng, K. Miller, F. Fitzal, J.M. Gil, H. Park, B. Linderholm, E. Bajetta, Z. Dayao, A. Prat, K. Ehrhardt, O. Metzger, A. Arahmani, E.H. Law, A.H. Partridge, L.A. Carey, A. Zoroufy, A.C. Dueck, P. O\u2019Brien, D. Hlauschek, A. DeMichele, E.L. Mayer\u00a0<\/p>\n

ESMO Open
\nVolume 10, Issue 6,\u00a0June 2025, 105120
\nhttps:\/\/doi.org\/10.1016\/j.esmoop.2025.105120<\/a><\/p>\n

\n

The future of surgical research<\/h4>\n

Michael Gnant<\/p>\n

British Journal of Surgery, Volume 112, Issue 6
\nJune 2025, znaf095
\nhttps:\/\/doi.org\/10.1093\/bjs\/znaf095<\/a><\/p>\n

\n

St. Gallen\/Vienna 2025
\nSummary of Key messages on therapy in Early Breast Cancer from the 2025 St. Gallen International Breast Cancer Conference (SGBCC)<\/h4>\n

Nina Ditsch, Michael Gnant, Christoph Thomssen, Nadia Harbeck<\/p>\n

Breast Care\u00a0
\nPublished online: May 03, 2025
\nhttps:\/\/doi.org\/10.1159\/000546080<\/a><\/p>\n

\n

BRCA1\/2\u00a0and Other Predisposition Genes in High-Risk Hormone Receptor+\/Human Epidermal Growth Factor Receptor 2\u2013 Breast Cancer Treated With Endocrine Therapy With or Without Palbociclib: A Secondary PENELOPE-B Study Analysis<\/h4>\n

Eric Hahnen, Jan Hauke, Karen Gelmon, Frederik Marme, Corinna Ernst, Miguel Martin, Michael Untch, Herve Bonnefoi, Erik Knudsen, Seock-Ah Im, Angela DeMichele, Laura Van\u2019t Veer, Sung-Bae Kim, Harry Bear, Nicole McCarthy, Kerstin Rhiem, Nicholas Turner, Agnieszka Witkiewicz, Federico Rojo, Martin Filipits, Lesley-Ann Martin, Peter A. Fasching, Christian Schem, Kerstin Becker, Jos\u00e9 A. Garc\u00eda-S\u00e1enz, Catherine M. Kelly, Toralf Reimer, Masakazu Toi, Hope S. Rugo, Carsten Denkert, Michael Gnant, Andreas Makris, Yuan Liu, Olga Valota, Barbel Felder, Karsten Weber, Valentina Nekljudova, and Sibylle Loibl<\/p>\n

JCO Precision Oncology
\nApril 10, 2025
\nhttps:\/\/doi.org\/10.1200\/PO-24-00742<\/a><\/p>\n

\n

Augmenting Insufficiently Accruing Oncology Clinical Trials Using Generative Models: Validation Study<\/h4>\n

Samer El Kababji; Nicholas Mitsakakis; Elizabeth Jonker; Ana-Alicia Beltran-Bless; Gregory Pond; Lisa Vandermeer; Dhenuka Radhakrishnan; Lucy Mosquera; Alexander Paterson; Lois Shepherd; Bingshu Chen; William Barlow; Julie Gralow; Marie-France Savard; Christian Fesl; Dominik Hlauschek; Marija Balic; Gabriel Rinnerthaler; Richard Greil; Michael Gnant; Mark Clemons; Khaled El Emam<\/p>\n

J Med Internet Res 2025 | vol. 27 | e66821
\nhttps:\/\/www.jmir.org\/2025\/1\/e66821<\/a><\/p>\n

\n

CAMBRIA-1 & CAMBRIA-2 phase III trials: camizestrant versus standard endocrine therapy in ER+\/HER2\u2013 early breast cancer<\/h4>\n

Erika P. Hamilton, Sibylle Loibl, Thomas Bachelot, Michael Gnant, Naoki Niikura, Yeon Hee Park, Sara M. Tolaney, Barbara Pistilli, Priya Rastogi, Kamal S. Saini, Ioanna Gioni, Simon Johnston, Raquel Nunes, Angela Quintana, Mary Stuart, Emilia Syta, Andrew Walding, Teresa Klinowska and Ingrid A. Mayer<\/p>\n

Future Oncology
\nPublished online: 27 Feb 2025
\nhttps:\/\/doi.org\/10.1080\/14796694.2025.2459548<\/a><\/p>\n

\n

Validation of the CTS5 in four prospective, multicenter, randomized ABCSG trials<\/h4>\n

Kerstin\u00a0Wimmer, Dominik\u00a0Hlauschek, Marija\u00a0Balic, Georg\u00a0Pfeiler, Richard\u00a0Greil, Christian F.\u00a0Singer, Stefan\u00a0Halper, G\u00fcnther\u00a0Steger, Christoph\u00a0Suppan, Simon Peter\u00a0Gampenrieder, Ruth\u00a0Helfgott, Daniel\u00a0Egle, Martin\u00a0Filipits, Raimund\u00a0Jakesz, Lidija\u00a0S\u00f6lkner, Christian\u00a0Fesl, Michael\u00a0Gnant, Florian\u00a0Fitzal on behalf of the\u00a0Austrian Breast & Colorectal Cancer Study Group<\/p>\n

The Breast, Volume 80104415 April 2025
\nAvailable online 19 February 2025
\nhttps:\/\/doi.org\/10.1016\/j.breast.2025.104415<\/a><\/p>\n

\n

Impact of adding palbociclib on treatment adherence to ongoing adjuvant endocrine treatment in the global randomized PALLAS randomized trial in patients with early breast cancer<\/h4>\n

Eileen Shinn \u00b7 David Zahrieh \u00b7 Angela DeMichele \u00b7 Nick Zdenkowski \u00b7 Julie Lemieux \u00b7 Jun Mao \u00b7 Vesna Bjelic\u2011Radisic \u00b7 Michelle J. Naughton \u00b7 Georg Pfeiler \u00b7 Karen Gelmon \u00b7 Justin M. Balko \u00b7 Daniel Egle \u00b7 Gabriele Zoppoli \u00b7 Tiffany Traina \u00b7 Miguel Martin Jimenez \u00b7 Silvia Antolin Novoa \u00b7 Tufia Haddad \u00b7 Arlene Chan \u00b7 Alistair Ring \u00b7 Antonio Wolff \u00b7 William Fraser Symmans \u00b7 Jose Ponce Lorenzo \u00b7 Dhanusha Sabanathan\u00b7 Hal J. Burstein \u00b7 Zbigniew Ireneusz Nowecki \u00b7 Gunda Pristauz\u2011Telsnigg \u00b7 Adam Brufsky \u00b7 Meritxell Bellet\u2011Ezquerra \u00b7 Theodoros Foukakis \u00b7 Yelena Novik \u00b7 Gabor Rubovszky \u00b7 Christian F. Singer \u00b7 Karoline Muehlbacher \u00b7 Otto Metzger Filho \u00b7 Theodora Goulioti \u00b7 Ernest Law\u00b7 Ann H. Partridge \u00b7 Lisa A. Carey \u00b7 Alex Zoroufy \u00b7 Dominik Hlauschek \u00b7 Christian Fesl \u00b7 Erica L. Mayer \u00b7 Michael Gnant<\/p>\n

Breast Cancer Research and Treatment
\n11 February 2025
\nhttps:\/\/doi.org\/10.1007\/s10549-025-07653-2<\/a><\/p>\n

\n

Dynamics of molecular heterogeneity in high-risk luminal breast cancer\u2014From intrinsic to adaptive subtyping<\/h4>\n

Carsten Denkert, Sivaramakrishna Rachakonda, Thomas Karn, Karsten Weber, Miguel Martin, Frederik Marm\u00e9, Michael Untch, Herv\u00e9 Bonnefoi, Sung-Bae Kim, Sabine Seiler, Harry D. Bear, Agnieszka K. Witkiewicz, Seock-Ah Im, Angela DeMichele, Anika Pehl, Laura van\u2019t Veer, Nicole McCarthy, Thorsten Stiewe, Paul Jank, Karen A. Gelmon, Jos\u00e9 A. Garc\u00eda-S\u00e1enz, Christina C. Westhoff, Catherine M. Kelly, Toralf Reimer, B\u00e4rbel Felder, Mireia Mel\u00e9 Oliv\u00e9 , Erik S. Knudsen, Nicholas Turner, Federico Rojo, Wolfgang D. Schmitt, Peter A. Fasching, Julia Teply-Szymanski, Zhe Zhang, Masakazu Toi, Hope S. Rugo, Michael Gnant, Andreas Makris, Johannes Holtschmidt, Valentina Nekljudova, and Sibylle Loibl<\/p>\n

Cancer Cell 43, 232\u2013247, February 10, 2025 , Published by Elsevier Inc.
\nhttps:\/\/doi.org\/10.1016\/j.ccell.2025.01.002<\/a><\/p>\n

\n

Outcomes in stage IIA versus stage IIB\/III in the PALLAS trial [ABCSG-42\/AFT-05\/PrE0109\/BIG-14-13])<\/h4>\n

A. DeMichele, A. C. Dueck, D. Hlauschek et al.<\/p>\n

Published 23 January 2025
\nBreast Cancer Research 27, 12
\nhttps:\/\/doi.org\/10.1186\/s13058-024-01941-3<\/a><\/p>\n

\n

Efficacy and Safety of CDK4\/6 Inhibitors: A Focus on HR+\/HER2\u2212 Early Breast Cancer<\/h4>\n

Eva Valentina Klocker, Daniel Egle, Rupert Bartsch, Gabriel Rinnerthaler, Michael Gnant<\/p>\n

Drugs
\nPublished:\u00a017 January 2025
\nhttps:\/\/doi.org\/10.1007\/s40265-024-02144-y<\/a><\/p>\n

\n

Neoadjuvant atezolizumab in combination with dual HER2 blockade plus epirubicin in women with early HER2-positive breast cancer: the randomized phase 2 ABCSG-52\/ATHENE trial<\/h4>\n

Gabriel Rinnerthaler,\u00a0Daniel Egle,\u00a0Rupert Bartsch,\u00a0Clemens A. Schmitt,\u00a0Andreas Petzer,\u00a0Marija Balic,\u00a0Edgar Petru,\u00a0Ursula Denison,\u00a0Christian F. Singer,\u00a0Vesna Bjelic-Radisic,\u00a0Simon Peter Gampenrieder,\u00a0Michael Knauer,\u00a0Karl Sotlar,\u00a0Christine Brunner,\u00a0Florian Posch,\u00a0Dominik Hlauschek,\u00a0Lidija S\u00f6lkner,\u00a0Zsuzsanna Bago-Horvath,\u00a0Martin Filipits,\u00a0Manuela Gili,\u00a0Magdalena Ritter,\u00a0Verena Wieser,\u00a0Carmen Albertini,\u00a0Nadja Zaborsky,\u00a0Lukas Weiss,\u00a0Maximilian Marhold,\u00a0Bruno Schneeweiss,\u00a0Renate Pusch,\u00a0Michael Gnant\u00a0&\u00a0Richard Greil\u00a0<\/p>\n

Nature Cancer
\nPublished:\u00a016 January 2025
\nhttps:\/\/doi.org\/10.1038\/s43018-024-00890-2<\/a><\/p>\n

\n

Drug-drug interactions between palbociclib and proton pump inhibitors in\u00a0early breast cancer: an exploratory analysis of PALLAS (ABCSG-42\/AFT-05\/BIG-14-13\/PrE0109)<\/h4>\n

Agostinetto, G. Pfeiler, D. Hlauschek, E.L. Mayer, M. Lambertini, E. de Azambuja, M. Bellet-Ezquerra, J.L. Meisel, G. Rubovszky, N. Zdenkowski, Y. Novik, M. Ruiz-Borrego, K.A. Gelmon, E.P. Mamounas, H. Iwata, D.R. Lu, L. Soelkner, C. Fesl, M. Gnant, A. DeMichele<\/p>\n

ESMO Open
\nVolume 10, Issue 1, January 2025, 104096
\nhttps:\/\/doi.org\/10.1016\/j.esmoop.2024.104096<\/a><\/p>\n

\n

HER2 and HER3 expression during neoadjuvant treatment of HER2-negative early breast cancer: potential for biomarker-driven sequencing of T-DXd and HER3-DXd<\/h4>\n

Christian Fridolin Singer, Stephan Wenzel Jahn, Dominik Hlauschek, Ulrike Maria Heber, Charlotte Mang-Manger, Daniel Egle, Marija Balic, Angelika Pichler, Georg Pfeiler, Stephanie Kacerovsky-Strobl, Christoph Suppan, Magdalena Ritter, Edgar Petru, Richard Greil, Zsuzsanna Bago-Horvath, Christine Deutschmann, G\u00fcnther Georg Steger, Michael Seifert, Florian Fitzal, Rupert Bartsch, Anu Santhanagopal, Jana Machacek-Link, Dalila Sellami, Magdalena Schwarz, Christian Fesl, Lidija S\u00f6lkner, Stephen Esker, Martin Filipits, Michael Gnant on behalf of the Austrian Breast and Colorectal Cancer Study Group Cancer Communications<\/p>\n

Cancer Communications 2025;1\u20135.
\n2025 Jan 6.\u00a0doi: 10.1002\/cac2.12657.\u00a0Online ahead of print.
\nhttps:\/\/doi.org\/10.1002\/cac2.12657<\/a><\/p>\n<\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":28699,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-publikationen.php","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-41126","page","type-page","status-publish","hentry"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-11 17:43:32","action":"delete","newStatus":"draft","terms":[],"taxonomy":"translation_priority","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages\/41126","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/comments?post=41126"}],"version-history":[{"count":2,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages\/41126\/revisions"}],"predecessor-version":[{"id":41164,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages\/41126\/revisions\/41164"}],"up":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages\/28699"}],"wp:attachment":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/media?parent=41126"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/tags?post=41126"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}