{"id":39130,"date":"2025-07-29T10:59:25","date_gmt":"2025-07-29T08:59:25","guid":{"rendered":"https:\/\/www.abcsg.org\/?page_id=39130"},"modified":"2026-03-17T16:57:45","modified_gmt":"2026-03-17T15:57:45","slug":"abcsg-65-defintive-overview-2","status":"publish","type":"page","link":"https:\/\/www.abcsg.org\/en\/abcsg-studien\/studies-open-for-enrollment\/abcsg-65-defintive\/abcsg-65-defintive-overview-2\/","title":{"rendered":"ABCSG 65 \/ DEFINITIVE Overview"},"content":{"rendered":"<p><strong>D<\/strong>iagnostic H<strong>E<\/strong>R2DX-guided treatment <strong>F<\/strong>or pat<strong>I<\/strong>e<strong>N<\/strong>ts w<strong>I<\/strong>th early-stage HER2-posi<strong>TIVE<\/strong> breast cancer<\/p>\n<p>An international, multicenter, prospective, two-arm, randomized, open-label Phase III study designed to demonstrate that personalized treatment decisions in HER2-positive early-stage breast cancer using the HER2DX\u00ae diagnostic test improve quality of life without compromising outcomes and survival rates.<\/p>\n<table class=\"studienmeta-public\">\n<tbody>\n<tr>\n<td>Study Start:<\/td>\n<td>(global): 11\/2024, \u00a0FPI 11\/2024<br \/>\n(national): 07\/2025<\/td>\n<\/tr>\n<tr>\n<td>Coordinating Investigator AT:<\/td>\n<td>Simon Gampenrieder, Salzburg<\/td>\n<\/tr>\n<tr>\n<td>Participants:<\/td>\n<td>315 (global), 61 (national)<\/td>\n<\/tr>\n<tr>\n<td>Study Design:<br \/>\n<em>(Click to enlarge)<\/em><\/td>\n<td><a  href=\"https:\/\/www.abcsg.org\/wp\/wp-content\/uploads\/2025\/07\/Design-ABCSG-65.jpg\" data-rel=\"lightbox-gallery-0\" data-rl_title=\"\" data-rl_caption=\"\" title=\"\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-39138 size-medium\" src=\"https:\/\/www.abcsg.org\/wp\/wp-content\/uploads\/2025\/07\/Design-ABCSG-65.jpg\" alt=\"Study Design:\n \" width=\"280\" height=\"140\" srcset=\"https:\/\/www.abcsg.org\/wp\/wp-content\/uploads\/2025\/07\/Design-ABCSG-65.jpg 900w, https:\/\/www.abcsg.org\/wp\/wp-content\/uploads\/2025\/07\/Design-ABCSG-65-280x140.jpg 280w, https:\/\/www.abcsg.org\/wp\/wp-content\/uploads\/2025\/07\/Design-ABCSG-65-768x384.jpg 768w\" sizes=\"auto, (max-width: 280px) 100vw, 280px\" \/><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Diagnostic HER2DX-guided treatment For patIeNts wIth early-stage HER2-posiTIVE breast cancer An international, multicenter, prospective, two-arm, randomized, open-label Phase III study designed to demonstrate that personalized treatment decisions in HER2-positive early-stage breast cancer using the HER2DX\u00ae diagnostic test improve quality of life without compromising outcomes and survival rates. Study Start: (global): 11\/2024, \u00a0FPI 11\/2024 (national): 07\/2025 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":39064,"menu_order":12,"comment_status":"closed","ping_status":"closed","template":"page-einzel-studie.php","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"class_list":["post-39130","page","type-page","status-publish","hentry"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-10-17 07:25:36","action":"delete","newStatus":"draft","terms":[],"taxonomy":"translation_priority","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages\/39130","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/comments?post=39130"}],"version-history":[{"count":10,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages\/39130\/revisions"}],"predecessor-version":[{"id":41241,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages\/39130\/revisions\/41241"}],"up":[{"embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/pages\/39064"}],"wp:attachment":[{"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/media?parent=39130"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.abcsg.org\/en\/wp-json\/wp\/v2\/tags?post=39130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}